In silico and in vitro evaluation of imatinib as an inhibitor for SARS-CoV-2Article Published on 2023-04-012023-07-08 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), [키워드] ACE2 acute respiratory disease Bcr-Abl tyrosine kinase inhibitor Betacoronavirus COVID-19 Imatinib molecular docking SARS-CoV-2 surface structural spike glycoprotein. Wuhan [DOI] 10.1080/07391102.2022.2045221 PMC 바로가기
A replication-competent smallpox vaccine LC16m8Δ-based COVID-19 vaccineArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome analysed antibody antibody titres BALB/c BALB/c mouse boost CD4 CD8 cellular cellular immunity coronavirus coronavirus disease COVID-19 COVID-19 vaccine Delta/B.1.617.2 variant of concern effective eight elicited emerging and re-Emerging coronaviruses glycoprotein homologous humoral Humoral immunity immunization Japanese LC16m8 less mice motif multifunctional neutralized Neutralizing activity patients with COVID-19 polybasic prime-boost immunization. provide recombinant replication-competent viral S-specific antibody S1/S2 cleavage site SARS-CoV-2 serum sample significantly lower Strains T-cell immune responses T-cell immunity T-cell Response the S protein Vaccine Vaccine development vaccine platform variant vector viral vectors virus Wuhan [DOI] 10.1080/22221751.2022.2122580 PMC 바로가기
Broad and durable antibody response after vaccination with inactivated SARS-CoV-2 in individuals with a history of 2003 SARS-CoV infection2003년 SARS-CoV 감염 이력이 있는 개인에서 비활성화된 SARS-CoV-2 백신 접종 후 광범위하고 지속적인 항체 반응Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] activity antibody Antibody Response Antigen Beta Delta dosage greater Heterologous heterologous immunization inactivated Inactivated vaccine individual naïve vaccinees neutralizing activities Neutralizing activity nucleoprotein omicron pseudovirus pseudoviruses RBD of SARS-CoV-2 receiving SARS-CoV SARS-CoV infection SARS-CoV-2 SARS-CoV-2 vaccine SARS-related coronaviruses second vaccination significantly higher suggested undetectable universal vaccine. vaccination Vaccine vaccinee vaccinees variant variants virus viruses were infected Wuhan [DOI] 10.1080/22221751.2022.2076613 PMC 바로가기 [Article Type] Article
Mapping post-traumatic stress disorder symptoms and quality of life among residents of Wuhan, China after the COVID-19 outbreak: A network perspectiveResearch article Published on 2022-12-012022-10-05 Journal: Journal of affective disorders [Category] 진단, [키워드] approach Attention changes in checklist Chinese Civilian Community conducted connection covariates COVID-19 COVID-19 outbreak cross-sectional cross-sectional survey emotional examined Follow-up General population initial lack life limitation mapping mental health network analysis objective outbreak pandemic participant Perspective Post-traumatic stress disorder Post-traumatic stress disorder symptoms Quality Quality of life Result self-report measure Study design Symptom Version were measured World Health Organization Wuhan Wuhan residents Wuhan, China [DOI] 10.1016/j.jad.2022.08.074 [Article Type] Research article
Molecular evidence for SARS-CoV-2 in samples collected from patients with morbilliform eruptions since late 2019 in Lombardy, northern ItalyArticle Published on 2022-12-012022-11-15 Journal: Environmental research [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG association B.1 Brazil circulation collected COVID-19 database detectable anti-SARS-CoV-2 antibodies downloaded emergence evaluated Evidence group highlight IgA antibodies IgG and IgM IgM individual Infection investigated Italy Laboratory lombardy measles molecular Mutation oropharyngeal swab outbreak pandemic Patient patients PCR positive positive patient producing Rash reported retrospective RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2. screened sequence sequence information Sequencing Spread strain subjects Surveillance syndrome tested Urine virus Wuhan [DOI] 10.1016/j.envres.2022.113979 PMC 바로가기
SARS-CoV-2 vaccine breakthrough reinfection in a health-care worker of Iraq: A case report이라크 의료 종사자에서 SARS-CoV-2 백신 획기적인 재감염: 사례 보고Case Reports Published on 2022-11-302022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 변종, [키워드] affected Breakthrough infection Case report circulating variants completion COVID-19 COVID-19 pandemic delta variant Effectiveness globe Health health worker health-care Infection Intervention Iraq Isolation many case many cases mediated immunity Patient question raised Reinfection reported Respiratory illness RT-PCR SARS-CoV-2 SARS-CoV-2 vaccine scarcity severe respiratory illness symptom severity the SARS-CoV-2 vaccinated individuals vaccination Vaccine vaccine breakthrough infection vaccine breakthrough infections vaccine-mediated immunity variants variants. Wuhan Wuhan, China [DOI] 10.1080/21645515.2022.2055947 PMC 바로가기 [Article Type] Case Reports
Evaluating correlates of protection for mix-match vaccine against COVID-19 VOCs with potential of evading immunityArticle Published on 2022-11-082022-11-15 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] appear Bayesian Beta ChAdOx1 Clinical efficacy Correlate of protection COVID-19 D614G Delta Delta VOC distribution Efficacy ENhance evaluate Evaluating finding Heterologous highlight homologous Immunity inversion Mix-match mRNA-1273 neutralizing antibody omicron pandemic phase 3 trial predicted Predictive previous study provide ranged reduction reductions in strain vaccination Vaccine variant Variant of concern. variants variants of concern VoC VOCs was used while Wuhan [DOI] 10.1016/j.vaccine.2022.10.011 PMC 바로가기
Antibody correlates of protection from SARS-CoV-2 reinfection prior to vaccination: A nested case-control within the SIREN studyArticle Published on 2022-11-012022-11-15 Journal: The Journal of Infection [Category] SARS, 진단, 치료기술, [키워드] age analysed anti-S anti-SARS-CoV-2 antibody association Case-control case-control study controls correlated fixed Gender identify Immunity Increasing infected individual Infection Linear regression Live virus logistic regression models Neutralising Antibodies no difference nucleocapsid occurred performed pre-vaccination protective effect pseudovirus reduced risk Reinfection required Result SARS-CoV-2 SARS-CoV-2 serology. serological serology serum sample significantly lower SIREN study tested titre titres vaccination Wuhan [DOI] 10.1016/j.jinf.2022.09.004 PMC 바로가기
Hamsters Protected from SARS-CoV-2 Delta Variant Challenge after Two Doses of Adjuvanted SARS-CoV-2 Recombinant Spike Protein (S-2P) and One Dose of Beta S-2PArticle Published on 2022-11-012022-11-15 Journal: The Journal of Infectious Diseases [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome Beta challenge coronavirus COVID-19 COVID-19 vaccine Delta dose Effectiveness hamster hamster challenge study highest live SARS-CoV-2 Live virus lung MVC-COV1901 neutralization Neutralizing antibody titer Omicron variant pathology prefusion PROTECT pseudovirus recombinant regimen S-2P SARS-CoV-2 SARS-CoV-2 delta SARS-CoV-2 vaccine spike Spike protein subunit Subunit vaccine suggested vaccination Vaccines variant Variant of concern. variants variants of concern virus Wuhan [DOI] 10.1093/infdis/jiac153 PMC 바로가기
Differences in environmental stability among SARS-CoV-2 variants of concern: both omicron BA.1 and BA.2 have higher stabilityArticle Published on 2022-11-012022-11-16 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 변종, [키워드] Beta calculated Characteristics Concentration contributing to Delta difference Disinfection Disinfection effectiveness Effectiveness Efficacy environmental stability evaluate evaluated Ex vivo exhibited Gamma in vitro inactivated Infection median omicron regression analysis risk SARS-CoV-2 SARS-CoV-2 variant Spread stability survival transmissibility of SARS-CoV-2 Transmission variant variants variants of concern virus Virus survival. virus titre VoC VOCs was determined were measured Wuhan Wuhan strain [DOI] 10.1016/j.cmi.2022.05.020 PMC 바로가기